Screening for endometrial carcinoma is not as satisfactory as screening for cancer of the cervix because of the inaccessibility of the uterine cavity. Pap smears detect only a small percentage of endometrial cancers.
There have been studies of other screening methods that can be performed in the doctor's office, with several showing the benefit of using endometrial biopsies to screen high-risk women who have no symptoms. This procedure is associated with some discomfort, however, and may not be cost-effective in the absence of risk factors . Routine annual screening for women without symptoms is not recommended.
